The nearest airport is HOG - Holguin Frank Pais Intl, located 27.6 km south of Santa Clara.
Other airports nearby include VTU - Las Tunas Hermanos Ameijeiras (66.3 km west), BYM - Bayamo Carlos Manuel De Cespedes (78.2 km south west), MZO - Manzanillo Sierra Maestra (116.6 km south west), SCU - Santiago De Cuba Antonio Maceo Intl (127.5 km south),