The nearest airport is CMW - Camaguey Ignacio Agramonte Intl, located 43.0 km north west of Santa María.
Other airports nearby include VTU - Las Tunas Hermanos Ameijeiras (65.2 km east), MZO - Manzanillo Sierra Maestra (107.7 km south east), BYM - Bayamo Carlos Manuel De Cespedes (127.6 km south east), HOG - Holguin Frank Pais Intl (133.5 km east),