The nearest airport is VTU - Las Tunas Hermanos Ameijeiras, located 43.6 km east of Guáimaro.
Other airports nearby include CMW - Camaguey Ignacio Agramonte Intl (65.9 km north west), MZO - Manzanillo Sierra Maestra (88.6 km south), BYM - Bayamo Carlos Manuel De Cespedes (104.9 km south east), HOG - Holguin Frank Pais Intl (111.6 km east),