The nearest airport is CFG - Cienfuegos Jaime Gonzalez, located 56.7 km south east of San Manuel.
Other airports nearby include SNU - Santa Clara Abel Santamaria (77.4 km east), VRA - Varadero Juan Gualberto Gomez Intl (90.9 km north west), CYO - Cayo Vilo Acuna Intl (139.9 km south west), HAV - Havana Jose Marti Intl (182.1 km west),